Highly Commended, BMA Medical Book Awards 2013 Sarcoidosis represents a major challenge for physicians-not just in respiratory medicine, but across a range of specialties. This book, with a multidisciplinary authorship of the highest standard, presents the most up-to-date thinking on all aspects of the condition, from epidemiology to clinical manifestations and treatment options. Full coverage is given to both respiratory and non-respiratory aspects. The basic science that underlies the disease and its progression is evaluated in detail, and placed into its correct clinical context. Possible future advances are covered in a concluding section. The editors-all leading figures in the field with international reputations-have compiled the definitive work on the subject in a single volume. The book is fully comprehensive and evidence based and will be an essential addition to the bookshelves of all whose practice involves the care and treatment of patients with sarcoidosis.

Highly Commended, BMA Medical Book Awards 2013 Sarcoidosis represents a major challenge for physicians-not just in respiratory medicine, but across a range of specialties. This book, with a multidisciplinary authorship of the highest standard, presents the most up-to-date thinking on all aspects of the condition, from epidemiology to clinical manifestations and treatment options. Full coverage is given to both respiratory and non-respiratory aspects. The basic science that underlies the disease and its progression is evaluated in detail, and placed into its correct clinical context. Possible future advances are covered in a concluding section. The editors-all leading figures in the field with international reputations-have compiled the definitive work on the subject in a single volume. The book is fully comprehensive and evidence based and will be an essential addition to the bookshelves of all whose practice involves the care and treatment of patients with sarcoidosis.

Bacteria have evolved with extraordinary abilities to regulate aspects of their behavior (such as gene expression) in response to signals in the intracellular and extracellular environment. Key to this are the diverse macromolecules (proteins or RNA) that sense change through direct interactions with chemical or physical stimuli. In recent years, there have been tremendous advances in understanding the structure and function of these signal receptors, and how interaction with the signal triggers changes in their activity and downstream events. For some systems, this understanding extends to the atomic level. In this unique book, an international team of experts reviews a selection of important model systems, providing a timely snapshot of the current state of research in the field. Sensory Mechanisms in Bacteria opens with an introductory chapter that reviews the diversity of signal recognition mechanisms, illustrating the breadth of the field. Subsequent chapters include descriptions

The lung forms an integral part of the body's immune system and is subject to a range of diseases which are either autoimmune in nature or have clear-cut immunological abnormalities. "Autoimmune Aspects of Lung Disease" provides a concise review of the lung's role in the immune system and a detailed account of both primary and secondary lung diseases which are characterised by immunological perturbation or frank autoimmunity. The volume presents a detailed, up-to-date account of disorders ranging from infection to neoplasia and is written in both an informative and stimulating style by a prestigious group of authors. The chapters are extensively referenced and provide numerous insights into the aetiopathogenesis and clinical features and treatment of immunologically-linked pulmonary disease. The book is intended as both an overview for physicians and scientists with an established interest in diseases of the lung, immunologists seeking to learn more about relevant disorders in the lung and general physicians, whether specialists or in training, seeking to enrich their knowledge of the links between the pulmonary and immune systems.

The third edition of this book provides new material on sleep disordered breathing, the newer methods of staging of lung cancer, interstitial lung diseases and infections all of which have developed in importance since the last edition of the book. The traditional areas of respiratory medicine remain strongly represented and the new edition contains many new radiological illustrations. The book contains integrated self-test questions, illustrations and detailed explanations. It is designed to educate as well as give answers to problems. The cases appear in random order and at varying levels of difficulty, just as patients present in practice. The Colour Review will appeal to a wide readership, ranging from senior medical students and post-registration trainees in internal medicine, to pulmonologists in training and practice, for examination revision and continuing education.